May 23, 2019 poor sleep quality and peptic ulcer disease pud, a condition when sores known as ulcers develop on the lining of your stomach or in the first part of your small intestine are. A peptic ulcer is an ulcer of one of those areas of the gastrointestinal tract that are usually acidic. Gitu, md, florida state university college of medicine family medicine. The formation of peptic ulcers depends on the presence of gastric juice ph and the decrease in mucosal defenses.
Introduction peptic ulcer disease represents a serious medical problem. It extends into the muscularis propria layer of the gastric epithelium. Peptic ulcer disease kalyanakrishnan ramakrishnan, md, frcse, and robert c. It usually occurs in the stomach and proximal duodenum. Peptic ulcers are small sores that form in the lining of the esophagus swallowing pipe, stomach, or duodenum the first part of the small intestine. Peptic ulcer disease gastroenterology jama jama network. Peptic ulcer disease pud is characterized by discontinuation in the inner lining of the gastrointestinal gi tract because of gastric acid secretion or pepsin.
Traditionally, a hypersecretory acidic environment together with dietary factors or stress were thought to. Pdf management of nsaidassociated peptic ulcer disease. Peptic ulcer disease including both gastric and duodenal ulcer form a substantial part of patients seeking surgical opinion worldwide. Clinical study of peptic ulcer disease peptic ulcer disease refers to painful sores or ulcers in the lining of the stomach or first part of the small intestine, called the duodenum. If you have peptic ulcer disease or another problem with digestion, you may be referred to a specialist called a gastroenterologist. A read is counted each time someone views a publication summary such as the title, abstract, and list of authors, clicks on a figure, or views or downloads the fulltext. Nonsteroidal antiinflammatory drugs nsaids and helicobacter pylori h. A peptic ulcer is a sore on the lining of the stomach or duodenum. Peptic ulcer disease home american academy of family.
They newly began in around 53 million people in 2014. Peptic ulcer disease journal articles managing inflammatory rheumatic conditions in the elderly what special considerations should be taken when managing elderly patients with chronic. The concept of acid in peptic ulcer disease, which was the basis of treatment of peptic ulcer was revolutionized by the discovery of h 2receptor antagonists, that led to the principle of acid suppression therapy for duodenal ulcer which followed decades of. The two most common types of peptic ulcer are called gastric ulcers and duodenal ulcers. About 15 million people in the united states have peptic ulcer disease. Interestingly, those at the highest risk of contracting peptic ulcer disease are those. A peptic ulcer, also known as pud or peptic ulcer disease, is an ulcer defined as mucosal erosions equal to or greater than 0. Salinas, md university of oklahoma health sciences center, oklahoma city, oklahoma p eptic. Clinical study of peptic ulcer disease allied academies. Case study peptic ulcer free download as powerpoint presentation. Peptic ulcer is a chronic disease affecting up to 10% of the worlds population. Diagnosis and treatment of peptic ulcer disease and h. Ulcers are typically caused by bacteria or as a side effect of antiinflammatory drugs, and the main. An overview of history, pathogenesis and treatment of.
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